Table 3 Summaries of the multiple regression models predicting ACSA, SEIQoL-DW and ADI scores in ALS groups. Significant effects are printed in bold

Country

2

0.15

0.859

2

7.30

0.001

2

6.55

0.002

Age

1

0.18

0.675

1

0.06

0.810

1

3.72

0.055

Sex

1

1.22

0.271

1

1.41

0.235

1

3.04

0.082

ALSFRS-R

1

5.07

0.025

1

1.47

0.226

1

20.03

< 0.001

Disease duration

1

2.76

0.098

1

0.33

0.563

1

8.27

0.004

Country x Age

2

0.45

0.640

2

1.33

0.265

2

0.47

0.627

Country x Sex

2

1.75

0.175

2

1.72

0.182

2

0.94

0.392

Country x ALSFRS-R

2

5.74

0.004

2

2.58

0.077

2

3.71

0.026

Country x Disease duration

2

0.36

0.697

2

0.69

0.501

2

0.28

0.756

Age x Gender

1

0.11

0.738

1

0.59

0.441

1

3.19

0.075

Age x ALSFRS-R

1

3.10

0.079

1

0.11

0.741

1

0.20

0.658

Age x Disease duration

1

0.01

0.923

1

0.01

0.936

1

0.43

0.512

Gender x ALSFRS-R

1

0.02

0.875

1

1.98

0.160

1

2.23

0.137

Gender x Disease duration

1

4.01

0.046

1

0.12

0.730

1

0.01

0.904

ALSFRS-R x Disease duration

1

0.18

0.675

1

0.41

0.524

1

0.74

0.390

Model statistics

F(20, 279) = 2.20,

p = 0.002, R² = 0.136, Adjusted R² = 0.074

 F(20, 269) = 1.78,

p = 0.023, R² = 0.117, Adjusted R² = 0.051

 F(20, 273) = 4.56,

p < 0.001, R² = 0.251, Adjusted R² = 0.196