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Table 3 Characteristics of the studies included in the review

From: Factors related to advance directives completion among cancer patients: a systematic review

Authors Year

Aim

Country

Methodology

Sample and setting

Wang et al. 2021 [36]

To describe the knowledge and preferences of ADs and EOL care decisions of patients with brain tumors

China

cross-sectional

Patients from Cancer Hospital, Chinese

316 Brain Tumor Patients

Cohen et al. 2021 [37]

To investigate of the potential association between ACP and hope in advanced cancer

USA

cross-sectional

672 patients with cancer from 17 medical oncology practices within the University of Pittsburgh Medical Center Hillman Cancer

Berkowitz et al. 2021 [38]

To investigate of components of ACP in patients with cancer as compared with patients with noncancer serious illness referred to palliative care

USA

cross-sectional

1,604 patients with cancer and 1,094 patients without cancer in Duke University Medical Center

Bar-Sela et al. 2021 [39]

To investigate of evaluate the barriers and motives among Israeli cancer patients regarding ACP

Israel

mixed-methods

109 Israeli advanced cancer patients from the Division of Oncology at Rambam

Rodenbach et al. 2020 [40]

To investigate of relationships between patients’ worry about dying and their illness understanding, treatment preferences, and ACP

USA

cross-sectional

672 patients with solid tumors at 17 cancer clinics in western Pennsylvania

Brown et al. 2016 [19]

To evaluate patients’ knowledge regarding ADs

USA

prospective study

110 gynecologic cancer patients from Anderson Gynecologic Oncology Clinic in Houston

Kish et al. 2000 [41]

To investigate of describe cancer patients admitted to an ICU with and without ADs

USA

prospective study

872 patients with Malignancy in Anderson Cancer Center

Dow et al. 2010 [42]

To investigate of determine with which of their physicians patients preferred to discuss ADs

USA

Qualitative/ Semi-structured interviews

75 patients with cancer in Virginia Commonwealth University Medical Center Hematology

Kubi et al. 2020 [43]

To investigate of oncology patients’ preferences surrounding ACP with a focus on the choice of which health care providers to have the conversation with and the timing of conversations

USA

cross-sectional

200 oncology patients from the surgical oncology and medical oncology units of Johns Hopkins Hospital

Saeed et al. 2019 [44]

investigate of effect of income and education on the completion of ADs

USA

cross-sectional

256 patients were had stage IV nonhematologic cancer or stage III cancer in the Rochester/Buffalo, New York, and Sacramento, California regions

Prater et al. 2019 [45]

investigate of determine the impact of advance care planning (ACPEOL) among a sample of hospice-referred patients with cancer

USA

retrospective cohort

1185 patients with a primary diagnosis of cancer from a Midwestern academic medical center

Bires et al. 2018 [46]

Investigate of understand the various challenges and personal beliefs regarding ACP through interviews with two groups: patients undergoing active cancer treatment and their oncology providers

USA

Qualitative/ semi-structured interview

10 oncology providers and 20 patients from 39 to 69 years in multispecialty, ambulatory care cancer center in the Atlantic region

McDonald et al. 2017 [31]

Investigate of awareness and prevalence of ADs among patients with advanced cancer undergoing active outpatient care and to determine factors associated with AD completion before and after the diagnosis of cancer

Canada

cross-sectional

395 patients with advanced solid tumor malignancy in Cancer Centre, University Health Network, Toronto

Kim et al. 2017 [47]

Investigate of undertaken to examine the extent to which cancer patient–caregiver dyads would utilize the K–AD and their level of agreement about EoL decisions

Korean

descriptive study

81 cancer patients in from one of two tertiary hospitals in Korea

Zheng et al. 2016 [13]

To investigate knowledge and attitudes of approving ADs and explore factors associated with willing to designate ADs among cancer patients in China

China

Qualitative/ semi-structured interview

753 in-patients with cancer in Two departments of oncology from two university hospitals

Tan and Jatoi et al. 2008 [48]

To assess current rates of ADs among patients with incurable pancreas cancer

USA

retrospective study

1,186 consecutive patients with unresectable pancreas cancer in Mayo Clinic in Rochester/Minnesota

True et al. 2005 [49]

Investigated of differences between African American and White patients with cancer in their use of spirituality to cope with their cancer and examined the role of spiritual coping in preferences at EOL

USA

study group

68 patients with an advanced stage of lung or colon cancer from the Albert Einstein Cancer Center

Seifart et al. 2020 [50]

Investigation of gender differences concerning the content, the desired time point, and the mode of initiation of EOL conversations in cancer patients

German

cross-sectional

186 female and male cancer patients in University Hospital Marburg

Zaros et al. 2013 [51]

To examine physician assessment of decisional capacity and the prevalence of EOL discussions during the terminal hospitalization of patients with advanced cancer

USA

retrospective cohort

145 cancer patients in the University of Michigan Hospital

Wallace et al. 2001 [52]

Investigation of the presence of an AD at admission to an intensive care unit (ICU) influenced the decision to initiate life support therapy in critically ill cancer patients

USA

case-control

872 patients treated in the Anderson Cancer Center ICU

Lin et al. 2019 [53]

Investigation of decision-making processes and drivers of receiving palliative care in ACP discussions from perspectives of advanced cancer patients, families and healthcare professionals in northern Taiwan

Taiwan

Qualitative/ Semi-structured interviews

45participants oncology unit and one hospice unit in a tertiary hospital

Sudore et al. 2018 [54]

Engaging Diverse English- and Spanish-Speaking Older Adults in Advance Care Planning The PREPARE Randomized Clinical Trial

USA

Clinical trial

986 English-speaking and Spanish-speaking older adults with chronic illness from 4 primary care clinics